Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2018; 10(1): 48-55
Published online Jan 15, 2018. doi: 10.4251/wjgo.v10.i1.48
Comparison between laparoscopic and open surgery for large gastrointestinal stromal tumors: A meta-analysis
Jian-Xin Cui, Yun-He Gao, Hong-Qing Xi, Ai-Zhen Cai, Ke-Cheng Zhang, Ji-Yang Li, Bo Wei, Lin Chen
Jian-Xin Cui, Yun-He Gao, Hong-Qing Xi, Ai-Zhen Cai, Ke-Cheng Zhang, Ji-Yang Li, Bo Wei, Lin Chen, Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Cui JX, Gao YH and Xi HQ contributed equally to this work; Wei B and Chen L conceived the project; Cui JX and Gao YH independently searched references and took charge of data extraction and statistical analysis; Xi HQ searched references and extracted the parameters from each study; Cai AZ, Zhang KC and Li JY participated in the manuscript revision; all authors read and approved the final manuscript.
Supported by National Program on Key Basic Research Project of China, No. 2014CBA02002; National Key Research and Development Plan, No. 2016YFC0905302; National Natural Science Foundation of China, Nos. 81672319 and 81602507; and Beijing Municipal Science and Technology Project, No. D131100005313010.
Conflict-of-interest statement: This work was presented as an e-poster at the 12th International Gastric Cancer Congress (IGCC), April 20-23, 2017. We have no financial relationship to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Lin Chen, MD, PhD, Professor, Department of General Surgery, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.
Telephone: +86-10-66938128 Fax: +86-10-66938128
Received: October 23, 2017
Peer-review started: October 24, 2017
First decision: November 23, 2017
Revised: December 4, 2017
Accepted: December 6, 2017
Article in press: December 6, 2017
Published online: January 15, 2018
Core Tip

Core tip: Whether laparoscopic resection is also effective and feasible for treatment of larger gastric gastrointestinal stromal tumors (GISTs) (> 5 cm) remains unknown. This meta-analysis collected up-to-date clinical data of comparison of laparoscopic and open resection for larger gastric GISTs (> 5 cm). Our results showed that laparoscopic resection is an upgraded minimal invasive technique with a shorter postoperative hospital stay and less intraoperative blood loss compared with open surgery in treating patients with larger GISTs.