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World J Gastrointest Oncol. Oct 15, 2021; 13(10): 1466-1474
Published online Oct 15, 2021. doi: 10.4251/wjgo.v13.i10.1466
Endoscopic papillectomy for ampullary adenomatous lesions: A literature review
Shu-Ling Li, Wen Li, Jian Yin, Zi-Kai Wang
Shu-Ling Li, Jian Yin, Department of Gastroenterology and Hepatology, The Fourth Medical Center, Chinese PLA General Hospital, Beijing 100048, China
Wen Li, Zi-Kai Wang, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Li SL and Wang ZK carried out a literature review for data collection and contributed to drafting this paper; Wang ZK, Li W and Yin J revised this article; All authors did the final approval of the version to be published.
Conflict-of-interest statement: Nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zi-Kai Wang, MD, PhD, Associated Chief Physician, Associate Professor, Deputy Director, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China. wangzikai301@126.com
Received: March 21, 2021
Peer-review started: March 21, 2021
First decision: May 7, 2021
Revised: June 2, 2021
Accepted: August 9, 2021
Article in press: August 9, 2021
Published online: October 15, 2021
Processing time: 206 Days and 5.7 Hours
Abstract

Ampullary adenomatous lesions of the gastrointestinal tract are rare and can be asymptomatic. Therefore, ampullary adenomas with malignant potential require prompt removal, regardless of whether they are adenomatous or carcinomatous lesions. Endoscopic papillectomy is a safe and effective alternative therapy to surgery to treat duodenal papillary lesions in selected patients. Accurate preoperative diagnosis and staging of ampullary adenomatous lesions are critical for predicting prognosis and determining the most appropriate therapeutic approach. Furthermore, the management and prevention of adverse events and endoscopic treatment for remnant or recurrent lesions and surveillance are essential for successful endoscopic management of ampullary adenomatous lesions. This literature review was based on PubMed and MEDLINE and focused on recent advancements in the endoscopic papillectomy technique to provide a comprehensive view of endoscopic papillectomy to treat ampullary adenomatous lesions.

Keywords: Ampullary adenomatous lesions; Endoscopic papillectomy; Endoscopic ultrasonography; Endoscopic retrograde cholangiopancreatography; Complications; Surveillance

Core Tip: The endoscopic papillectomy for ampullary adenomatous lesions are still controversial. This review mainly focused on the recent advancements of endoscopic papillectomy and then introduced the indication, endoscopic evaluation, treatment and related complications and surveillance for ampullary adenomatous lesions.