Published online Dec 15, 2019. doi: 10.4251/wjgo.v11.i12.1231
Peer-review started: February 22, 2019
First decision: June 4, 2019
Revised: September 1, 2019
Accepted: September 26, 2019
Article in press: September 26, 2019
Published online: December 15, 2019
Follicular dendritic cell (FDC) sarcoma/tumor is a rare malignant tumor of follicular dendritic cells, which is considered a low-grade sarcoma that can involve lymph nodes or extranodal sites. Conventional FDC sarcomas are negative for Epstein-Barr virus (EBV), whereas the inflammatory pseudotumor-like variant consistently shows EBV in the neoplastic cells.
We report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that received 3D laparoscopic right hepatectomy and open right hepatectomy separately.
EBV probe-based in situ hybridization and detection of immunohistochemical markers of FDC play an important role in the diagnosis and differential diagnosis of inflammatory pseudotumor-like FDC sarcoma. Complete surgical excision combined with regional lymphadenectomy may be effective in reducing the postoperative recurrence and metastasis and improving long-term survival rates.
Core tip: There have been 48 previously reported cases of inflammatory pseudotumor-like follicular dendritic cell (FDC) sarcoma, which occurs almost exclusively in the liver and spleen. Here we report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that were treated by 3D laparoscopic right hepatectomy and open right hepatectomy separately.