Improved diagnostic yield of endoscopic ultrasound-fine needle biopsy with histology specimen processing

Table 1 Baseline patient and procedural characteristics

	FNA alone (n = 17)	FNB alone (n = 56)	FNA with FNB (n = 33)	P value
Age, mean (range)	55.2 (30-75)	55.0 (23-84)	56.6 (37-76)	0.7502
Male, n (%)	5 (29.4)	24 (42.9)	15 (25.5)	0.5533
Needle type
FNA needle (Expect)	16	0	31	-
Franseen needle (Acquire)	0	50	32	-
Fork-tip needle (SharkCore)	0	3	0	-
Reverse bevel needle (ProCore)	0	1	1	-
Other1	0	1	3	-
Not documented	1	3	2	-
Needle passes, mean (range)	3.4 (1-5)	3.4 (1-8)	2.8 (1-8)	-

Multiple needle types were used in the same procedure.

¹Other needles include EZ shot FNA needle (Olympus) and Moray Micro Forceps (US endoscopy) through a 19-Gauge FNA needle. EUS: Endoscopic ultrasound; FNA: Fine needle aspiration; FNB: Fine needle biopsy.

Table 2 Indications for endoscopic ultrasound-guided fine needle aspiration and endoscopic ultrasound-guided fine needle biopsy

Indication (n = 106)	n (%)
Pancreatic mass	33 (31.1)
Gastric mass	19 (17.9)
Liver biopsy	15 (14.2)
Pancreatic cyst	14 (13.2)
Lymph node	6 (5.7)
Biliary	5 (4.7)
Extraluminal	4 (3.8)
Pancreatitis	4 (3.8)
Rectal	2 (1.9)
Small bowel	2 (1.9)
Mediastinal	1 (0.9)
Esophageal	1 (0.9)

Table 3 Diagnostic yield and specimen adequacy, n (%)

	Diagnostic yield	Specimen adequacy
FNA alone (n = 17)	8 (47.1)	9 (52.9)
FNB alone (n = 56)	48 (85.7)	50 (89.3)
FNA with FNB (n = 33)	28 (84.8)	28 (84.8)

FNA: Fine needle aspiration; FNB: Fine needle biopsy.