Evaluation of the diagnostic and therapeutic utility of retrograde through-the-scope balloon enteroscopy and single-balloon enteroscopy

Table 1 Patient demographics and clinical characteristics

	Enteroscope device
	Entire cohort	Retrograde SBE1	Retrograde TTSE2
Number of patients	75	49	26
	Mean (standard deviation)	Mean (standard deviation)	Mean (standard deviation)	P value
Age (yr)3	61.2 (17.6)	62.6 (16.5)	58.4 (19.6)	0.33
Body mass index3	29.0 (6.1)	28.7 (6.3)	29.6 (5.9)	0.55
Gender, n (%)				0.63
Female	43 (57.3)	27 (55.1)	16 (61.5)
Male	32 (42.7)	22 (44.9)	10 (38.5)
Ethnicity, n (%)				0.91
Hispanic	27 (36.0)	18 (36.7)	9 (34.6)
Other non-hispanic	10 (13.3)	7 (14.3)	3 (11.5)
White	38 (50.7)	24 (49.0)	14 (53.9)
Indication3				0.63
Iron deficiency anemia, n (%)	41 (50.6)	28 (51.9)	13 (48.2)
Overt GI bleeding	37 (45.7)	23 (42.6)	14 (51.9)
Abdominal pain	17 (21.1)	7 (13.0)	10 (37.0)
Diarrhea	7 (8.6)	4 (7.4)	3 (11.1)
FAP screening	2 (2.5)	2 (3.7)	0 (0)

¹Single balloon enteroscopy.

²Through the scope.

³Some patients have 2 indications. GI: Gastrointestinal; FAP: Familial adenomatous polyposis; SBE: Single balloon enteroscopy; TTSE: Through–the-scope enteroscopy.

Table 2 Prior video capsule endoscopy

	Entire cohort	Retrograde SBE1	Retrograde TTSE2
Number of procedures	81	54	27
Prior video capsule, n (%)				1.00
No	23 (28.4)	15 (27.8)	8 (29.6)
Yes	58 (71.6)	39 (72.2)	19 (70.4)
Video capsule positive finding, n (%)				0.30
No	6 (10.3)	4 (10.3)	2 (7.4)
Yes	52 (89.7)	35 (89.7)	17 (92.6)

¹Single balloon enteroscopy.

²Through the scope enteroscopy. SBE: Single balloon enteroscopy; TTSE: Through–the-scope enteroscopy.

Table 3 Procedure data including routes, diagnostic yield, findings, and interventions

	Enteroscope device
	Entire cohort	Retrograde SBE1	Retrograde TTSE2
Number of procedures	81	54	27
	Mean (SD)	Mean (SD)	Mean (SD)	P value3
Duration of procedure	86.2 (34.2)	91.9 (34.2)	70.5 (30.7)	0.04
Depth of the scope insertion	82.1 (64.1)	92.5 (70.0)	64.6 (49.0)	0.08
Successful procedure with diagnostic yield, n (%)	n = 64	n = 41	n = 23	0.39
Normal	43 (67.2)	26 (63.4)	17 (73.9)
Positive finding	21 (32.8)	15 (36.6)	6 (26.1)
Intervention performed, n (%)				0.38
No	65 (80.3)	45 (83.3)	20 (74.1)
Yes	16 (19.8)	9 (16.7)	7 (25.9)
Failed (2011-2018), n (%)	17 (21.0)	13 (24.1)	4 (14.8)	0.33
Terminal ileum not intubated	9 (11.1)	8 (14.8)	1 (3.7)
Insertion < 20 cm	8 (9.9)	5 (9.3)	3 (11.1)
Years	Failed/procedure	Failed/procedure	Failed/procedure
2011-2012	5/14	5/14	-
2013-2014	4/27	4/22	0/5
2015-2016	6/26	3/11	3/15
2017-2018	2/14	1/7	1/7

¹Single balloon enteroscopy.

²Through the scope enteroscopy.

³Compares retrograde single balloon enteroscopy and retrograde through–the-scope enteroscopy.