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Copyright ©The Author(s) 2018.
World J Gastrointest Endosc. Oct 16, 2018; 10(10): 259-266
Published online Oct 16, 2018. doi: 10.4253/wjge.v10.i10.259
Figure 1
Figure 1 Altered Ca2+ homeostasis- change from physiologic intracellular transient Ca2+ spikes to pathologically sustained global Ca2+ rise, can lead to significantly lower pH values and cause early enzyme activation.
Figure 2
Figure 2 Sterile injury causes acinar cell necrosis, the release of intracellular contents, and activation of damage-associated molecular patterns that further determine pancreatic injury.
Figure 3
Figure 3 Activation of pattern recognition receptors.