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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2015; 7(4): 346-353
Published online Apr 16, 2015. doi: 10.4253/wjge.v7.i4.346
Published online Apr 16, 2015. doi: 10.4253/wjge.v7.i4.346
Endoscopic diagnosis and management of type I neuroendocrine tumors
Yuichi Sato, Department of Gastroenterology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8121, Japan
Author contributions: Sato Y solely contributed to this manuscript.
Conflict-of-interest: The author declares that no financial or other conflicts of interest exist in relation to the content of this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yuichi Sato, MD, Department of Gastroenterology, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi-dori, Niigata 951-8121, Japan. yuichi@med.niigata-u.ac.jp
Telephone: +81-25-2272207 Fax: +81-25-2270776
Received: September 5, 2014
Peer-review started: September 6, 2014
First decision: November 27, 2014
Revised: December 9, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: April 16, 2015
Peer-review started: September 6, 2014
First decision: November 27, 2014
Revised: December 9, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: April 16, 2015
Core Tip
Core tip: The incidence of type I gastric neuroendocrine tumors (TI-GNETs) has significantly increased, TI-GNETs are the most frequently diagnosed of all GNETs, accounting for about 70%-80%. Endoscopically, TI-GNETs are present as small (< 10 mm), polypoid lesions or, more frequently, as smooth, rounded submucosal lesions. Especially, narrow band imaging and high resolution magnification endoscopy may be helpful for the endoscopic diagnosis of TI-GNETs. TI-GNETs tend to display a nearly benign behavior and a low risk of progression or metastasis in spite of submucosal invasion. Therefore, endoscopic submucosal dissection is a feasible technique for the removal of TI-GNETs.