Sajid MS, Ahamd A, Miles WF, Baig MK. Systematic review of oncological outcomes following laparoscopic vs open total mesorectal excision. World J Gastrointest Endosc 2014; 6(5): 209-219 [PMID: 24891934 DOI: 10.4253/wjge.v6.i5.209]
Corresponding Author of This Article
Muhammad Shafique Sajid, Surgical Specialist Registrar, Department of General, Endoscopic and Laparoscopic Colorectal Surgery, Western Sussex Hospitals NHS Trust, Worthing Hospital, Washington Suite, North Wing, West Sussex, BN11 2DH, United Kingdom. surgeon1wrh@hotmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. May 16, 2014; 6(5): 209-219 Published online May 16, 2014. doi: 10.4253/wjge.v6.i5.209
Systematic review of oncological outcomes following laparoscopic vs open total mesorectal excision
Muhammad Shafique Sajid, Adil Ahamd, William FA Miles, Mirza Khurrum Baig
Muhammad Shafique Sajid, Adil Ahamd, William FA Miles, Mirza Khurrum Baig, Department of General, Endoscopic and Laparoscopic Colorectal Surgery, Western Sussex Hospitals NHS Trust, Worthing Hospital, Worthing, West Sussex, BN11 2DH United Kingdom
Author contributions: All authors contributed substantially in literature search, data extraction, trial selection, statistical analysis, and final drafting of this article; Sajid MS contributed to idea conception, data analysis, data interpretation, draft writing; Ahmad A contributed to draft writing; Miles WFA contributed to data confirmation, data interpretation, draft writing and supervising the study.
Correspondence to: Muhammad Shafique Sajid, Surgical Specialist Registrar, Department of General, Endoscopic and Laparoscopic Colorectal Surgery, Western Sussex Hospitals NHS Trust, Worthing Hospital, Washington Suite, North Wing, West Sussex, BN11 2DH, United Kingdom. surgeon1wrh@hotmail.com
Telephone: +44-1903-205111 Fax: +44-1903-285010
Received: November 29, 2013 Revised: February 27, 2014 Accepted: March 11, 2014 Published online: May 16, 2014
Core Tip
Core tip: Based upon the findings of this systematic review of eleven randomized trial on 2143 patients of rectal cancer, there is a higher risk of surgical site infection, higher risk of incomplete total mesorectal resection and prolonged length of hospital stay following open total mesorectal excision (OTME) compared to laparoscopic total mesorectal excision (LTME). The number of harvested lymph nodes, tumour recurrence and risk of positive resection margins were statistically similar in both groups. In addition, the operative complications, anastomotic leak and mortality were comparable between LTME and OTME. LTME appears to have clinically and oncologically measurable advantages over OTME in patients with primary resectable rectal cancer.
