Factors predicting adverse short-term outcomes in patients with acute cholangitis undergoing ERCP: A single center experience

doi:10.4253/wjge.v6.i3.74

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Mar 16, 2014 (publication date) through Apr 26, 2024

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Mar 16, 2014; 6(3): 74-81
Published online Mar 16, 2014. doi: 10.4253/wjge.v6.i3.74

Factors predicting adverse short-term outcomes in patients with acute cholangitis undergoing ERCP: A single center experience

Udayakumar Navaneethan, Norma G Gutierrez, Ramprasad Jegadeesan, Preethi GK Venkatesh, Madhusudhan R Sanaka, John J Vargo, Mansour A Parsi

Udayakumar Navaneethan, Norma G Gutierrez, Ramprasad Jegadeesan, Preethi GK Venkatesh, Madhusudhan R Sanaka, John J Vargo, Mansour A Parsi, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, United States

Author contributions: Navaneethan U contributed to study concept and design, paper preparation and critical revisions; Gutierrez N, Jegadeesan R and Venkatesh PGK contributed to data monitoring and paper preparation; Sanaka M, Vargo J and Parsi M contributed to study concept, design, and critical revisions.

Supported by The American College of Gastroenterology Grant to Navaneethan U

Correspondence to: Mansour A Parsi, MD, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, United States. parsim@ccf.org

Telephone: +1-216-5020981 Fax: +1-216-4446305

Received: July 31, 2013
Revised: October 10, 2013
Accepted: November 12, 2013
Published online: March 16, 2014

Core Tip

Core tip: We investigated the effect of timing of endoscopic retrograde cholangiopancreatography (ERCP) on clinical outcomes defined as persistent organ failure and/or 30-d mortality, and length of hospital stay in patients with acute cholangitis. We observed that an American Society of Anesthesiology physical classification score > 3, presence of systemic inflammatory response syndrome and door to ERCP time greater than 72 h are associated with adverse clinical outcomes and prolonged length of hospital stay in patients with acute cholangitis.