Published online Aug 16, 2013. doi: 10.4253/wjge.v5.i8.398
Revised: May 15, 2013
Accepted: June 5, 2013
Published online: August 16, 2013
Core tip: Gastrointestinal bleeding and bowel perforations are known complications of Ehlers-Danlos syndrome (EDS) type IV Tissue fragility and hemorrhage tendency pose diagnostic as well as therapeutic dilemmas for both surgeons and gastroenterologists. We performed an upper gastrointestinal endoscopy and ileoscopy in a bleeding patient with history of EDS type IV. The upper endoscopy procedure was uneventful with minimal air used for luminal distension. A small bowel perforation was found. This case highlights the tissue fragility and serosal tears that can occur upon slight handling. Conservative management proved the best course of action.