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World J Gastrointest Endosc. Jun 16, 2021; 13(6): 161-169
Published online Jun 16, 2021. doi: 10.4253/wjge.v13.i6.161
Best practices for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis
Simcha Weissman, Mohamed Ahmed, Matthew R Baniqued, Dean Ehrlich, James H Tabibian
Simcha Weissman, Mohamed Ahmed, Matthew R Baniqued, Department of Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, NJ 07047, United States
Dean Ehrlich, UCLA Vatche and Tamar Manoukian Division of Digestive Diseases, Los Angeles, CA 91342, United States
James H Tabibian, Director of Endoscopy, Division of Gastroenterology, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA 91342, United States
Author contributions: Weissman S, Baniqued MR, and Ahmed M assisted with manuscript preparation and editing; Weissman S, Ehrlich D, and Tabibian JH critically revised the manuscript; Tabibian JH provided direct supervision and guidance; Weissman S and Tabibian JH are the article guarantors; all authors agree to the final version of this manuscript.
Conflict-of-interest statement: Nothing to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: James H Tabibian, MD, PhD, Health Sciences Clinical Associate Professor, David Geffen School of Medicine at UCLA, Olive View-UCLA Medical Center, 14445 Olive View Drive, 2B-182, Sylmar, CA 91342, United States. jtabibian@dhs.lacounty.gov
Received: January 27, 2021
Peer-review started: January 27, 2021
First decision: April 6, 2021
Revised: April 14, 2021
Accepted: May 21, 2021
Article in press: May 21, 2021
Published online: June 16, 2021
Core Tip

Core Tip: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) represents an important etiology of acute pancreatitis and is the most common major adverse event post-ERCP. Nevertheless, gaps in knowledge remain, as do large variations in clinical practice. Best practices with respect to the prevention of PEP continue to evolve as new evidence becomes available. Herein, we review the literature regarding PEP to increase awareness of this entity, facilitate best practices in PEP prevention and subsequent management, and ultimately improve clinical outcomes.