Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2021; 13(5): 115-124
Published online May 16, 2021. doi: 10.4253/wjge.v13.i5.115
Impact of intragastric balloon on blood pressure reduction: A retrospective study in Eastern North Carolina
Gbeminiyi Olanrewaju Samuel, Karissa Lambert, Elijah Asagbra, Glenn Harvin, Eric Ibegbu
Gbeminiyi Olanrewaju Samuel, Glenn Harvin, Eric Ibegbu, Division of Gastroenterology, East Carolina University, Greenville, NC 27834, United States
Karissa Lambert, Department of Internal Medicine, Brody School of Medicine, East Carolina University, Greenville, NC 27834, United States
Elijah Asagbra, Department of Health Services and Information Management, East Carolina University, College of Allied Health Sciences, Greenville, NC 27834, United States
Author contributions: Samuel GO and Lambert K collected and managed data, communicated with institutional review board, prepared study initiation activities, and helped with the writing of the manuscript; Asagbra E analyzed the data and helped with writing of the manuscript; Harvin G reviewed and helped with writing of the manuscript; Ibegbu E managed and provided data, reviewed and helped with writing of the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: This study was exempt from Institutional Review Board review after Institutional Review Board review (UMCIRB 19-001002).
Informed consent statement: A waiver of informed consent was obtained as the data are anonymized and the risk of the identification is low.
Conflict-of-interest statement: No relevant conflicts of interest exist for all authors.
Data sharing statement: Statistical codes, and dataset available from the corresponding author at
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Gbeminiyi Olanrewaju Samuel, MD, Academic Fellow, Division of Gastroenterology, East Carolina University, 2100 Stantonsburg Road, Greenville, NC 27834, United States.
Received: August 25, 2020
Peer-review started: August 25, 2020
First decision: December 11, 2020
Revised: December 26, 2020
Accepted: April 7, 2021
Article in press: April 7, 2021
Published online: May 16, 2021
Core Tip

Core Tip: Obesity is one of the leading causes of preventable life-years lost among Americans. Adults who have obesity compared with adults at a healthy weight have an increased risk of developing serious health conditions including hypertension. The treatment of hypertension in obesity is complicated by a high prevalence of resistant hypertension, as well as unpredictable hemodynamic effects of many medications. Weight loss stabilizes neurohormonal activity and causes clinically significant reductions in blood pressure. While lifestyle interventions can improve blood pressure, they fail to consistently yield sustained weight loss and have not demonstrated long-term benefits. Weight loss promotes dramatic declines in blood pressure and attenuation of long-term cardiovascular risk.