Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 16, 2019; 11(12): 589-595
Published online Dec 16, 2019. doi: 10.4253/wjge.v11.i12.589
Published online Dec 16, 2019. doi: 10.4253/wjge.v11.i12.589
Eosinophilic cholangitis: A case report of diagnostically challenging eosinophilic infiltrative biliary obstruction
Amar Dodda, Shiro Urayama, Department of Internal Medicine/Division of Gastroenterology and Hepatology, University of California–Davis, Sacramento, CA 95817, United States
Karen Matsukuma, Department of Pathology and Laboratory Medicine, University of California–Davis, Sacramento, CA 95817, United States
Author contributions: Dodda A reviewed the literature and contributed to manuscript drafting; Matsukuma K evaluated the biopsy specimens and provided analysis/images of relevant findings, contributed to the manuscript drafting; Urayama S performed the procedures, reviewed the literature, contributed to manuscript drafting and provided oversight for important intellectual content.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Amar Dodda, MD, Advanced Endoscopy Fellow, Department of Internal Medicine/Division of Gastroenterology and Hepatology, University of California–Davis, 4150 V St, Suite 3500, Sacramento, CA 95817, United States. amardb@gmail.com
Telephone: +1-312-5600650
Received: June 8, 2019
Peer-review started: June 10, 2019
First decision: August 2, 2019
Revised: October 17, 2019
Accepted: November 4, 2019
Article in press: November 5, 2019
Published online: December 16, 2019
Peer-review started: June 10, 2019
First decision: August 2, 2019
Revised: October 17, 2019
Accepted: November 4, 2019
Article in press: November 5, 2019
Published online: December 16, 2019
Core Tip
Core tip: Eosinophilic cholangitis is a rare cause of benign biliary strictures. The diagnosis is based predominantly on histopathologic findings in the setting of excluding malignancy, particularly in older age group. Previously, no quantitative eosinophilic threshold has been discussed in establishing the diagnosis of eosinophilic cholangitis, and hence the diagnosis is based on exclusion and suggestive findings. This case report provides the first look at eosinophils per high power field to help define eosinophilic cholangitis.