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Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jan 16, 2019; 11(1): 22-30
Published online Jan 16, 2019. doi: 10.4253/wjge.v11.i1.22
Pancreatoscopy: An update
Luca De Luca, Alessandro Repici, Adea Koçollari, Francesco Auriemma, Mario Bianchetti, Benedetto Mangiavillano
Luca De Luca, Gastroenterology and Digestive Endoscopy Unit, Ospedali Riuniti Marche Nord, Piazzale Cinelli, Pesaro 61121, Italy
Alessandro Repici, Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Research Hospital, Rozzano 20089, Italy
Alessandro Repici, Benedetto Mangiavillano, Humanitas University, Pieve Emanuele 20090, Italy
Adea Koçollari, Gastroenterology Unit, University Medical Center “Mother Theresa” Hospital, Tirana 1000, Albania
Francesco Auriemma, Mario Bianchetti, Benedetto Mangiavillano, Gastrointestinal Endoscopy Unit, Humanitas Mater Domini, Castellanza 21053, Italy
Author contributions: All authors contributed equally to this manuscript.
Conflict-of-interest statement: All authors have no conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Luca De Luca, MD, Doctor, Gastroenterology and Digestive Endoscopy Unit, Ospedali Riuniti Marche Nord, Piazzale Cinelli 1, Pesaro 61121, Italy. lucadeluca1210@gmail.com
Telephone: +39-721-362288 Fax: +39-721-362285
Received: September 28, 2018
Peer-review started: September 28, 2018
First decision: October 23, 2018
Revised: December 21, 2018
Accepted: December 29, 2018
Article in press: December 30, 2018
Published online: January 16, 2019
Core Tip

Core tip: Multiple modalities are available for the investigation of pancreatic diseases, such as magnetic resonance cholangiopancreatography, computed tomography, transabdominal ultrasound, endoscopic retrograde cholangiopancreatography, and endoscopic ultrasound. Per-oral pancreatoscopy was initially described in 1976. The available data suggests that in selected patients pancreatoscopy plays an important role in indeterminate pancreatic duct strictures and in evaluating the main pancreatic duct for intraductal papillary mucinous neoplasms following endoscopic ultrasound-fine needle aspiration prior to surgical treatment. Considering its therapeutic role, per-oral pancreatoscopy with lithotripsy has achieved a high rate of ductal clearance in patients with chronic calcific pancreatitis.