Case Report
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2017; 9(2): 99-104
Published online Feb 16, 2017. doi: 10.4253/wjge.v9.i2.99
Combination of concurrent endoscopic submucosal dissection and modified peroral endoscopic myotomy for an achalasia patient with synchronous early esophageal neoplasms
Sha Shi, Kuangi Fu, Xin-Qian Dong, Yu-Jing Hao, Sen-Lin Li
Sha Shi, Xin-Qian Dong, Yu-Jing Hao, Sen-Lin Li, Department of Gastroenterology, Liaocheng People’s Hospital, Liaocheng 252000, Shandong Province, China
Kuangi Fu, Department of Gastroenterology, Kanma Memorial Hospital, Tochigi 325-0046, Japan
Author contributions: All authors contributed to the manuscript.
Institutional review board statement: This study was reviewed and approved by Liaocheng People’s Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Sen-Lin Li, Department of Gastroenterology, Liaocheng People’s Hospital, No. 67 West Dongchang Road, Liaocheng 252000, Shandong Province, China. lisenlin6201@163.com
Telephone: +86-635-8277306 Fax: +86-635-8277306
Received: October 4, 2016
Peer-review started: October 7, 2016
First decision: November 10, 2016
Revised: December 5, 2016
Accepted: January 2, 2017
Article in press: January 3, 2016
Published online: February 16, 2017
Abstract

Achalasia is generally accepted as a condition associated with an increased risk for developing esophageal squamous cell carcinoma. In our paper, we introduced an achalasia patient combined with synchronous early esophageal neoplasms. We performed a combination of concurrent endoscopic submucosal dissection (ESD) and peroral endoscopic myotomy (POEM). No complications other than postoperative pain that needed morphine treatment for two days had occurred. Dysphagia was significantly improved. Neither reflux nor cough occurred. The short-term efficacy and safety of our case is favorable and suggests that concurrent ESD and POEM could be a treatment option to such patients.

Keywords: Achalasia, Early esophageal neoplasm, Endoscopic submucosal dissection, Modified peroral endoscopic myotomy

Core tip: Achalasia is generally accepted as a condition associated with an increased risk for esophageal squamous cell carcinoma. However, cases of multiple synchronous neoplastic lesions in an achalasia patient had been rarely reported. In this paper, we performed a combination of concurrent endoscopic submucosal dissection (ESD) and peroral endoscopic myotomy (POEM) on one patient suffering from esophageal achalasia for more than six years and esophageal neoplasia lesions for one month. The short-term efficacy and safety of our case is favorable and it suggests that concurrent ESD and POEM could be an option of treatment to this kind of patients.