Gurung A, Jaffe PE, Zhang X. Duodenal polyposis secondary to portal hypertensive duodenopathy. World J Gastrointest Endosc 2015; 7(17): 1257-1261 [PMID: 26634042 DOI: 10.4253/wjge.v7.i17.1257]
Corresponding Author of This Article
Xuchen Zhang, MD, PhD, Pathology and Laboratory Medicine Service, VA CT Healthcare System, 950 Campbell Ave, West Haven, CT 06516, United States. xuchen.zhang@yale.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Nov 25, 2015; 7(17): 1257-1261 Published online Nov 25, 2015. doi: 10.4253/wjge.v7.i17.1257
Duodenal polyposis secondary to portal hypertensive duodenopathy
Ananta Gurung, Philip E Jaffe, Xuchen Zhang
Ananta Gurung, Xuchen Zhang, Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, United States
Ananta Gurung, Department of Pathology, Royal Columbian Hospital, New Westminster, British Columbia V3L 3W7, Canada
Philip E Jaffe, Gastroenterology Center of Connecticut, Hamden, CT 06518, United States
Xuchen Zhang, Pathology and Laboratory Medicine Service, VA CT Healthcare System, West Haven, CT 06516, United States
Author contributions: Jaffe PE performed esophagogastroduodenoscopy; Gurung A and Zhang X performed histopathological examination; Gurung A wrote the initial draft of the manuscript; the final manuscript was reviewed and revised by Jaffe PE and Zhang X.
Institutional review board statement: Case reports do not require examination and are considered exempt by the Yale University Institutional Review Board. Ethical considerations were upheld and patient personal information was protected.
Informed consent statement: Written informed consent was obtained for all interventions and follow up.
Conflict-of-interest statement: The authors declare that there is no conflict of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Xuchen Zhang, MD, PhD, Pathology and Laboratory Medicine Service, VA CT Healthcare System, 950 Campbell Ave, West Haven, CT 06516, United States. xuchen.zhang@yale.edu
Telephone: +1-203-9325711 Fax: +1-203-9374704
Received: April 28, 2015 Peer-review started: April 30, 2015 First decision: July 26, 2015 Revised: October 2, 2015 Accepted: October 16, 2015 Article in press: October 19, 2015 Published online: November 25, 2015
Abstract
Portal hypertensive duodenopathy (PHD) is a recognized, but uncommon finding of portal hypertension in cirrhotic patients. Lesions associated with PHD include erythema, erosions, ulcers, telangiectasia, exaggerated villous pattern and duodenal varices. However, duodenal polyposis as a manifestation of PHD is rare. We report a case of a 52-year-old man who underwent esophagogastroduodenoscopy and was found with multiple small duodenal polyps ranging in size from 1-8 mm. Biopsy of the representative polyps revealed polypoid fragments of duodenal mucosa with villiform hyperplasia lined by reactive duodenal/gastric foveolar epithelium and underlying lamina propria showed proliferating ectatic and congested capillaries. The features were diagnostic of polyps arising in the setting of PHD.
