Yang HC, Qu W. Diagnostic and therapeutic review of a rare gastric inflammatory fibroid polyps case with distinctive features: A case report. World J Gastrointest Endosc 2025; 17(5): 106074 [DOI: 10.4253/wjge.v17.i5.106074]
Corresponding Author of This Article
Wei Qu, MD, Department of Gastroenterology, Qingdao Traditional Chinese Medicine Hospital, Qingdao Hiser Hospital Affiliated of Qingdao University, No. 4 Renmin Road, Qingdao 266000, Shandong Province, China. quwei604@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. May 16, 2025; 17(5): 106074 Published online May 16, 2025. doi: 10.4253/wjge.v17.i5.106074
Diagnostic and therapeutic review of a rare gastric inflammatory fibroid polyps case with distinctive features: A case report
Hong-Chao Yang, Wei Qu
Hong-Chao Yang, Wei Qu, Department of Gastroenterology, Qingdao Traditional Chinese Medicine Hospital, Qingdao Hiser Hospital Affiliated of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Yang HC assisted in the procedure and collected and organized the relevant data; Qu W performed the diagnosis and the surgery; all of the authors read and approved the final version of the manuscript to be published.
Supported by Shandong Province Traditional Chinese Medicine Science and Technology Youth Project, No: 2021Q057.
Informed consent statement: The researchers involved have signed the informed consent form.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Qu, MD, Department of Gastroenterology, Qingdao Traditional Chinese Medicine Hospital, Qingdao Hiser Hospital Affiliated of Qingdao University, No. 4 Renmin Road, Qingdao 266000, Shandong Province, China. quwei604@163.com
Received: February 24, 2025 Revised: March 31, 2025 Accepted: April 17, 2025 Published online: May 16, 2025 Processing time: 77 Days and 20.8 Hours
Abstract
BACKGROUND
Inflammatory fibroid polyps (IFPs) are generally considered as benign and relatively rare mesenchymal gastrointestinal tract tumors. IFPs can occur in any part of the gastrointestinal tract but are most prevalent in the stomach, particularly in the gastric antrum. With a low incidence in clinical practice and a lack of distinct endoscopic features, the preoperative diagnosis rate of IFP is disappointingly low, often leading to missed diagnoses or misdiagnoses.
CASE SUMMARY
A 43-year-old man, hospitalized with abdominal pain and distension, underwent his first gastroscopy in 2020, which revealed chronic superficial erosive gastritis. From 2021 to 2022, his condition progressed from antral ulcers to a 2.0 cm gastric antrum bulge of an unclear nature. After proton pump inhibitor treatment, the lesion shrank but did not heal completely. Following a thorough assessment using magnifying endoscopy with narrow-band imaging, gastric-enhanced computed tomography, and endoscopic ultrasonography, endoscopic submucosal dissection was performed on the identified lesion. A subsequent postoperative pathological examination conclusively diagnosed the lesion as an IFP. At 6 months follow-up, no recurrence or metastasis was observed, with good mucosal scar healing.
CONCLUSION
Through using multiple diagnostic and therapeutic test results, an IFP with an unusual morphology could be identified.
Core Tip: This article presents a rare case of inflammatory fibroid polyp (IFP) in the gastric antrum, tracking a dynamic change in the lesion from gastritis to a bulge. Advanced diagnostic methods such as magnifying endoscopy with narrow-band imaging, gastric-enhanced computed tomography, and endoscopic ultrasonography were combined for diagnosis and treatment. Postoperative pathological examination and immunohistochemistry findings confirmed the diagnosis. Endoscopic submucosal dissection is a safe and effective treatment with almost no recurrence. This case report may prompt clinicians to consider IFP when detecting bulge lesions during gastroscopy and to utilize multiple methods for diagnosis and evaluation.
