Published online Jan 28, 2017. doi: 10.4254/wjh.v9.i3.119
Peer-review started: August 29, 2016
First decision: October 8, 2016
Revised: November 8, 2016
Accepted: December 1, 2016
Article in press: December 2, 2016
Published online: January 28, 2017
Core tip: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality. Evidence shows that diet relates to HCC risk and may also have a protective role. Several dietary factors such as vegetables, cereals, fruits, white meat and fish have been found to be inversely associated with HCC risk, whereas a positive correlation has been found with red meat and dietary sugar intakes. The increasing HCC incidence makes its prevention an urgent matter and diet intervention represent an attractive potential. Dietary modifications are found to protect against HCC, however, new studies from well-designed and large prospective trials are required to confirm these results.