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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jun 28, 2015; 7(12): 1708-1717
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1708
Published online Jun 28, 2015. doi: 10.4254/wjh.v7.i12.1708
Hepatocellular carcinoma in Asia: Prevention strategy and planning
Sara Ashtari, Mohamad Amin Pourhoseingholi, Afsaneh Sharifian, Mohamad Reza Zali, Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985717413, Iran
Author contributions: Sharifian A and Zali MR designed the research; Pourhoseingholi MA designed and checked an edited the paper as a correspondence; Ashtari S performed the research and write the paper.
Supported by Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences.
Conflict-of-interest: The authors declared do not have anything to disclose regarding funding of conflict-of-interest with respect to this manuscript.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mohamad Amin Pourhoseingholi, PhD, Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tabnak St, Yaman Ave, Velenjak, Tehran 1985717413, Iran. amin_phg@yahoo.com
Telephone: +98-21-22432515 Fax: +98-21-22432517
Received: September 17, 2014
Peer-review started: September 20, 2014
First decision: November 27, 2014
Revised: December 31, 2014
Accepted: May 26, 2015
Article in press: May 27, 2015
Published online: June 28, 2015
Peer-review started: September 20, 2014
First decision: November 27, 2014
Revised: December 31, 2014
Accepted: May 26, 2015
Article in press: May 27, 2015
Published online: June 28, 2015
Core Tip
Core tip: In this current review, the burden and incidence of hepatocellular carcinoma (HCC) in Asian countries, risk factors and prevention of HCC are discussed. Infection of hepatitis B virus (HBV) is the main cause of HCC in Asia continent, where the virus is endemic and vertical transmission is common. Japan, Saudi Arabia, Egypt and Pakistan are exception due to of high prevalence of HCV infection. The main challenge which still present in Asia, is the high prevalence of chronic hepatitis. So, HBV and HCV prevention is the key strategy to decrease the incidence and burden of HCC in Asia.