Systematic Review
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World J Hepatol. May 27, 2014; 6(5): 347-357
Published online May 27, 2014. doi: 10.4254/wjh.v6.i5.347
Central hepatectomy for centrally located malignant liver tumors: A systematic review
Ser Yee Lee
Ser Yee Lee, Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore 169608, Singapore
Ser Yee Lee, Department of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore
Ser Yee Lee, Duke - National University of Singapore Graduate Medical School, Singapore 169857, Singapore
Author contributions: Lee SY solely contributed to this paper.
Correspondence to: Dr. Ser Yee Lee, MBBS, MMed, MSc, FAMS, FRCS(Ed), Department of Surgical Oncology, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore.
Telephone: +65-64368000  Fax: +65-62257559
Received: December 4, 2013
Revised: February 23, 2014
Accepted: May 8, 2014
Published online: May 27, 2014
Core Tip

Core tip: Central hepatectomy, defined as anatomical segment 4, 5, 8 ± 1 liver resection, is a promising parenchymal-preserving procedure in patients with centrally located liver malignancies. Based on current evidence, it appears to be safe and comparable in both perioperative, early and long term surgical and oncological outcomes when compared to patients undergoing traditional resections such as hemi-/extended hepatectomy.