Published online Feb 27, 2014. doi: 10.4254/wjh.v6.i2.92
Revised: December 16, 2013
Accepted: January 15, 2014
Published online: February 27, 2014
Core tip: This is the first study to evaluate the association between hepatitis C and the most frequently inherited monogenic liver diseases (hereditary hemochromatosis, alpha-1 antitrypsin deficiency, Gilbert’s syndrome, and Wilson’s disease) and their causative mutations. This case-control study revealed an association between hepatitis C and the mutation that causes Wilson’s disease. In addition, biochemical data analysis revealed an association between hepatitis C and the mutation that causes Gilbert’s syndrome.