Brief Article
Copyright ©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Hepatol. Oct 27, 2013; 5(10): 584-588
Published online Oct 27, 2013. doi: 10.4254/wjh.v5.i10.584
Risk factors for liver fibrosis among human immunodeficiency virus monoinfected patients using the FIB4 index in Morocco
Mohamed Tahiri, Mustapha Sodqi, Fatima Ez Zahra Lahdami, Latifa Marih, Hassan Lamdini, Wafaa Hliwa, Ahd Oulad Lahcen, Wafaa Badre, Fouad Haddad, Abdelfetah Chakib, Ahmed Bellabah, Rhimou Alaoui, Kamal Marhoum El Filali
Mohamed Tahiri, Fatima Ez Zahra Lahdami, Wafaa Hliwa, Wafaa Badre, Fouad Haddad, Ahmed Bellabah, Rhimou Alaoui, Department of Hepato-Gastro-Enterology, Ibn Rochd Hospital University Center, Casablanca 20270, Morocco
Mustapha Sodqi, Latifa Marih, Hassan Lamdini, Ahd Oulad Lahcen, Abdelfetah Chakib, Kamal Marhoum El Filali, Department of Infectious Diseases, Ibn Rochd Hospital University Center, Casablanca 20270, Morocco
Author contributions: Tahiri M and Sodqi M contributed equally to this paper, with significant contributions from Lahdami FEZ, Marih L, Lamdini H, Hliwa W, Lahcen AO, Badre W, Haddad F, Chakib A, Bellabah A, Alaoui R and El Filali KM.
Correspondence to: Mohamed Tahiri, PhD, Department of Hepato-Gastro-Enterology, Ibn Rochd Hospital University Center, 187 Lotissement Mandarona Sidi Maarouf, Casablanca 20270, Morocco. docteurtahirimohamed@yahoo.fr
Telephone: +212-67-7561214 Fax: +212-67-65437686
Received: April 13, 2013
Revised: August 31, 2013
Accepted: September 18, 2013
Published online: October 27, 2013
Core Tip

Core tip: We evaluated, for the first time in Morocco, the prevalence and risk factors of significant hepatic fibrosis in Moroccan human immunodeficiency virus (HIV) monoinfected patients using the FIB4 score which represents a noninvasive, composite index that is a validated measure of hepatic fibrosis. FIB4 score > 1.45 was found in 15.5% of Moroccan HIV monoinfected patients. Age, HIV viremia > 75 copies/mL and CD4 count < 200 cells/mm3 are associated with liver fibrosis. Gender, duration of HIV infection, glycemia, use of antiretroviral therapy and antiretroviral therapy duration were not associated with significant fibrosis.