Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jan 27, 2024; 16(1): 12-16
Published online Jan 27, 2024. doi: 10.4254/wjh.v16.i1.12
Metabolomics in liver diseases: A novel alternative for liver biopsy?
Yasuo Tanaka
Yasuo Tanaka, Department of Gastroenterology, National Center for Global Health and Medicine, Tokyo 162-8655, Japan
Author contributions: Tanaka Y contributed to the writing, and editing the manuscript, and review of literature.
Supported by JSPS KAKENHI, No. JP21K07906.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yasuo Tanaka, MD, PhD, Chief Doctor, Department of Gastroenterology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. ytanaka@hosp.ncgm.go.jp
Received: November 9, 2023
Peer-review started: November 9, 2023
First decision: November 27, 2023
Revised: December 5, 2023
Accepted: December 19, 2023
Article in press: December 19, 2024
Published online: January 27, 2024
Core Tip

Core Tip: Metabolomics, a rapidly emerging technology, offers a non-invasive alternative to conventional blood tests and transient elastography with magnetic resonance imaging or ultrasonography for fibrosis staging. I consider the article titled “Metabolomics in chronic hepatitis C: Decoding fibrosis grading and underlying pathways” by Ferrasi et al, published in the latest issue of the World J Hepatol. I review prior studies concerning the role of metabolomics in diagnosing hepatitis C virus-related liver fibrosis and establishing a foundation for non-invasive diagnostic techniques.