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World J Hepatol. May 8, 2016; 8(13): 591-596
Published online May 8, 2016. doi: 10.4254/wjh.v8.i13.591
Innovative surgical approaches for hepatocellular carcinoma
Riccardo Memeo, Nicola de’Angelis, Vito de Blasi, Zineb Cherkaoui, Oronzo Brunetti, Vito Longo, Tullio Piardi, Daniele Sommacale, Jacques Marescaux, Didier Mutter, Patrick Pessaux
Riccardo Memeo, Vito de Blasi, Zineb Cherkaoui, Jacques Marescaux, Didier Mutter, Patrick Pessaux, Department of Digestive Surgery, University Hospital of Strasbourg, 67091 Stra-sbourg, France
Riccardo Memeo, Vito de Blasi, Zineb Cherkaoui, Jacques Marescaux, Didier Mutter, Patrick Pessaux, IRCAD, Research Institute Against Cancer of the Digestive Tract, 67091 Strasbourg, France
Riccardo Memeo, Vito de Blasi, Zineb Cherkaoui, Jacques Marescaux, Didier Mutter, Patrick Pessaux, IHU-Strasbourg, Institute for Image-Guided Surgery, 67091 Strasbourg, France
Riccardo Memeo, Patrick Pessaux, Inserm U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, 67091 Strasbourg, France
Nicola de’Angelis, Unit of Digestive, Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Henri Mondor Hospital, AP-HP, 94010 Créteil, France
Nicola de’Angelis, Université Paris-Est, Val de Marne UPEC, 94010 Créteil, France
Oronzo Brunetti, Medical Oncology Unit, Cancer institute “Giovanni Paolo II”, 70100 Bari, Italy
Vito Longo, Medical Oncology Unit, Hospital “Di Miccoli”, 70124 Barletta, Italy
Tullio Piardi, Daniele Sommacale, Service de Chirurgie Générale, Digestive et Endocrinienne, Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims, Université de Reims Champagne-Ardenne, 51000 Reims, France
Author contributions: Memeo R, de’Angelis N, de Blasi V and Cherkaoui Z performed the study conception and design; Brunetti O, Longo V and Piardi T acquired the data; Sommacale D and Marescaux J analyzed the data; Marescaux J, Mutter D and Pessaux P reviewed the paper.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors con-tributed their efforts in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Riccardo Memeo, MD, PhD, Depart-ment of Digestive Surgery, University Hospital of Strasbourg, 1 Place de l'Hopital, 67091 Strasbourg, France. riccardo.memeo@chru-strasbourg.fr
Telephone: +33-3-69550552 Fax: +33-3-69550532
Received: February 26, 2016
Peer-review started: February 29, 2016
First decision: March 23, 2016
Revised: March 30, 2016
Accepted: April 14, 2016
Article in press: April 18, 2016
Published online: May 8, 2016
Abstract

Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide, with an increasing diffusion in Europe and the United States. The management of such a cancer is continuously progressing and the objective of this paper is to evaluate innovation in the surgical treatment of HCC. In this review, we will analyze the modern concept of preoperative management, the role of laparoscopic and robotic surgery, the intrao-perative use of three dimensional models and augme-nted reality, as well as the potential application of fluore-scence.

Keywords: Hepatocellular carcinoma, Liver resection, Hepatectomy, New prespectives, Innovative surgical approaches

Core tip: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide, with an increas-ing diffusion in Europe and the United States. The mana-gement of such a cancer is continuously progressing and the objective of this paper is to evaluate innovation in the surgical treatment of HCC.