Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stem Cells. Sep 26, 2020; 12(9): 897-921
Published online Sep 26, 2020. doi: 10.4252/wjsc.v12.i9.897
Dental stem cells: The role of biomaterials and scaffolds in developing novel therapeutic strategies
Cornelia Larissa Granz, Ali Gorji
Cornelia Larissa Granz, Ali Gorji, Epilepsy Research Center, Westfälische Wilhelms-Universität Münster, Münster 48149, Germany
Ali Gorji, Department of Neurosurgery and Department of Neurology, Westfälische Wilhelms-Universität, Münster 48149, Germany
Ali Gorji, Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran 1996836111, Iran
Ali Gorji, Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran
Author contributions: Granz CL and Gorji A contributed to the conception and design of the study; Granz CL contributed to writing and drafting of the manuscript; Gorji A contributed to critical revision of the final draft of the manuscript; all authors approved the final version of the manuscript.
Conflict-of-interest statement: There is no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Ali Gorji, MD, Full Professor, Epilepsy Research Center, Westfälische Wilhelms-Universität Münster, Domagkstr 11, Münster 48149, Germany.
Received: May 4, 2020
Peer-review started: May 4, 2020
First decision: May 24, 2020
Revised: June 5, 2020
Accepted: August 16, 2020
Article in press: August 16, 2020
Published online: September 26, 2020
Core Tip

Core Tip: Dental stem cells have been used for different types of cell transplantation therapies, including teeth, bone, and neural tissue regeneration. In planning for successful tissue engineering toward organ-specific regeneration, choosing an appropriate scaffold that mimics the extracellular matrix in native tissue and loaded with suitable biomolecules to boost dental stem cell functions is of utmost importance.