Expression of growth hormone receptor and its mRNA in hepatic cirrhosis

Table 1 Dynamic alteration of RCC, R_T and Kd in cirrhotic liver tissues

Time	RCC (%)		RT (fmol/mg protein)		Kd (nM)
	Control Group	Model Group	Control Group	Model Group	Control Group	Model Group
3rd week	1.29 ± 0.23	1.56 ± 0.35	75.8 ± 5.1	55.2 ± 4.5b	0.62 ± 0.03	0.61 ± 0.07
6th week	1.19 ± 0.21	10.8 ± 2.5ab	77.3 ± 4.3	42.6 ± 2.1ab	0.64 ± 0.05	0.58 ± 0.06
9th week	1.16 ± 0.18	20.2 ± 3.6ab	74.9 ± 3.9	30.8 ± 1.9ab	0.61 ± 0.09	0.60 ± 0.04
12th week	1.27 ± 0.25	28.0 ± 4.3ab	73.2 ± 5.4	17.5 ± 2.5ab	0.60 ± 0.08	0.59 ± 0.07
15th week	1.13 ± 0.24	15.2 ± 2.6ab	71.5 ± 4.9	20.8 ± 1.6b	0.58 ± 0.06	0.61 ± 0.09

^aP < 0.05 vs a previous time point,

^bP < 0.05 vs control group. RCC: Relative content of collagen (%) indicating severity of liver fibrosis; R_T: Total binding capacity of receptors (fmol/mg protein) corre-sponding to the quantity of receptors; K_d: Dissociation constant in equilibrium (nM) which is equal to the affinity of receptors.