Relationship between expression of CD105 and growth factors in malignant tumors of gastrointestinal tract and its significance

Table 1 Relations between MVD and TGF-β1 (under 400×)

Grade of TGF-β1 staining	n	%	MVD	P value
+++~++	21	38.18	23.22 ± 5.8	< 0.01a
+	9	16.36	17.56 ± 7.2	> 0.05b
-	25	45.46	17.46 ± 3. 9	< 0.01c
Total	55	100

^aP < 0.01, TGF-β1 +++ group vs. + group,

^bP > 0.05, TGF-β1 + group vs. - group,

^cP < 0.01, TGF-β1, group vs. +++ group.

Table 2 Relations between VEGF/MVD and clinical pathological parameters in colorectal carcinoma (under 100×)

Clinical pathological parameters	Cases (n)	VEGF	Px value	MVD (CD105)	P value
Histological grade
Well differentiation	1	18.50		143.1
Moderate differentiation	38	22.28 ± 14.49	> 0.05	144.8 ± 31.9	> 0.05
Poor differentiation	5	21.89 ± 14.44		146.4 ± 47.4
Infiltrating depth
Serous membrane (-)	5	9.37 ± 4.79	< 0.05	119.0 ± 17.2	= 0.05
Serous membrane (+)	39	22.55 ± 12.32		150.0 ± 32.7
Lymph node metastasis
(-)	24	14.76 ± 9.62	< 0.01	126.3 ± 20.8	< 0.01
(+)	20	27.31 ± 12.17		167.7 ± 30.3
Dukes stage
A	3	9.37 ± 4.79	< 0.01	119.0 ± 17.2	< 0.01
B	16	17.00 ± 10.37		129.3 ± 22.1
C and D	25	27.31 ± 12.16		167.7 ± 30.3