The role of endotoxin, TNF-α, and IL-6 in inducing the state of growth hormone insensitivity

Table 1 Serum GH levels in LPS injected rats at different time points and control rats

	n	GH levels (ng/mL)
Control	6	2.19 ± 0.48
1 h	6	1.85 ± 0.37a
2 h	6	1.95 ± 0.45a
4 h	6	1.76 ± 0.27a
8 h	6	1.79 ± 0.27a
12 h	6	1.77 ± 0.20a
24 h	6	1.79 ± 0.55a

^aStatistically no difference compared with control rats.

Table 2 Serum TNF-α and IL-6 levels in LPS injected rats at different time points and control rats

	n	TNF-α levels (pg/mL)	IL-6 levels (pg/mL)
Control	6	< 20	< 8
1 h	6	342.80 ± 50.01	1438.74 ± 323.07
2 h	6	75.81 ± 11.50	1678.03 ± 126.57
4 h	6	< 20	1332.67 ± 120.95
8 h	6	< 20	142.59 ± 48.07
12 h	6	< 20	48.75 ± 10.57
24 h	6	< 20	46.82 ± 11.64