Basic Research
Copyright ©The Author(s) 2002.
World J Gastroenterol. Jun 15, 2002; 8(3): 515-519
Published online Jun 15, 2002. doi: 10.3748/wjg.v8.i3.515
Table 1 The effect of IH764-3 on 3H-TdR incorporation (-x±s)
Dosage (μg·mL-1)CpmInhibitory rate (%)
019749 ± 7222
1018339 ± 53447.1
2014147 ± 1850b28.4
309125 ± 916b53.8
405313 ± 426b73.1
Table 2 Apoptotic rates of HSCs exposed IH764-3 with different doses by Annexin-V/PI (%)
Time doses0 μg·mL-110 μg·mL-120 μg·mL-130 μg·mL-140 μg·mL-1
12 hr0.32.23.76.715.1
48 hr2.36.79.315.119.7
Table 3 Percentage of apoptotic HSCs exposed to IH764-3 (30 μg·mL-1) at different time points by Annexin-V/PI (%)
Time0 hr12 hr24 hr48 hr72 hr
Apoptosis rate0.36.710.315.119.6
Table 4 Fluorescence index of caspase-3 protein in HSCs (-x±s)
Dosage (μg·mL-1)Caspase-3P value
0175.6 ± 22.5
10215.1 ± 26.9< 0.01
20231.6 ± 28.6< 0.01
30304.7 ± 30.7< 0.01
40338.9 ± 32.1< 0.01