Field Population-based blocking treatment of esophageal epithelia dysplasia

Table 1 Age distribution of detection rates of MEED, SEED I, SEED II, NEC, and EC by EBC screening

Histology Grade	Age										Total		OR
	40-		45-		50-		55-		60-
	n	Rate%	n	Rate%	n	Rate%	n	Rate%	n	Rate%	n	Rate%
Normal	2703	50.50	1578	43.83	1094	39.10	945	35.59	746	30.09	7021	41.92	0.60
MEED	1574	29.40	1100	31.76	928	33.17	882	33.22	862	34.77	5346	31.92	1.18
SEED I	820	15.32	626	18.08	550	19.66	572	21.54	611	24.65	3179	19.98	1.61
SEED II	208	3.89	151	4.36	166	5.93	167	6.29	174	7.02	866	5.17	1.80
NEC	28	0.52	39	1.13	29	1.04	43	1.62	33	1.33	172	1.03	2.56
EC	20	0.37	29	0.84	31	1.11	46	1.73	53	2.14	179	1.07	5.78
Total	5353		3463		2789		2655		2479		16748

Table 2 Effect of blocking treatment of MEED and SEED cases by ZSP, CT, and PLACEBO after three year medication

Group		No. subjects	EC Diagnosed			Incidence Rates (%)	Block Rates (%)
			EBC Re-screening	Registration	Total
MEE	Treatment	1566	10	18	28	1.79
	Control	3780	26	58	84	2.22
	Total	5346	36	76	112	2.10	19.37
SEED	Treatment	1396	17	11	28	2.01
	Control	3649	36	66	102	3.85
	Total	4045	53	77	130	3.21	47.79

Table 3 Results of blocking treatment of SEED I and SEED II cases by ZSP and PLACEBO after three years of medication

Group		No. subjects	No. EC Diagnosed	Incidence Rates (%)	Block Rates (%)
SEED I	Treatment	1206	20	1.66
	Control	1973	49	2.48
	Total	3179	69	2.17	33.06
SEED II	Treatment	279	8	2.87
	Control	587	53	9.03
	Total	866	61	7.04	68.22