Original Research
Copyright ©The Author(s) 1997.
World J Gastroenterol. Mar 15, 1997; 3(1): 27-30
Published online Mar 15, 1997. doi: 10.3748/wjg.v3.i1.27
Table 1 Demographic data and endoscopic findings in patients with and without hiatus hernia
Patients with HH (n = 71)Patients withoutHH (n = 126)P value
Age (yr)
Patients with esophagitis51.1 ± 1.540.7 ± 2.9< 0.001
Patients without esophagitis51.8 ± 4.241.0 ± 2.2< 0.001
Sex (n, f/m)25/4650/76> 0.05
Heartburn (%)80.289.6> 0.05
Regurgitation (%)54.354.8> 0.05
Chest pain (%)60.661.1> 0.05
Smoker (%)21.125.4> 0.05
Alcohol consumer (%)36.627.0> 0.05
Endoscopic findings (%)
Normal42.372.2< 0.001
Grade I-II esophagitis42.326.2< 0.05
Grade III-IV esophagitis15.41.6< 0.001
Table 2 Gastroesophageal reflux parameters in patients with and without hiatus hernia (¯x ± s)
RE (n = 64)PR (n = 37)PhR (n = 84)PhRE (n = 12)
Patients with HH
% time of reflux
24-h18.8 ± 15.414.9 ± 9.82.5 ± 0.23.9 ± 2.6
Upright17.9 ± 5.014.4 ± 9.32.7 ± 2.24.4 ± 3.7
Supine19.1 ± 2.215.1 ± 0.02.1 ± 3.53.6 ± 4.2
No. of episodes > 5 min
24-h9.1 ± 4.37.5 ± 3.20.9 ± 1.42.6 ± 4.1
Upright5.8 ± 4.44.2 ± 3.20.5 ± 1.01.5 ± 1.3
Supine3.3 ± 2.13.2 ± 2.30.3 ± 0.61.5 ± 1.8
Patients without HH
% time of reflux
24-h17.1 ± 4.813.3 ± 6.72.7 ± 2.21.5 ± 1.7
Upright18.9 ± 3.57.0 ± 8.03.4 ± 2.80.3 ± 0.5
Supine13.5 ± 1.72.7 ± 2.21.5 ± 3.01.1 ± 1.6
No. of episodes > 5 min
24-h10.5 ± 8.06.1 ± 3.50.9 ± 1.42.0 ± 2.7
Upright8.1 ± 6.94.5 ± 3.00.5 ± 1.01.6 ± 2.0
Supine2.3 ± 2.11.6 ± 1.40.3 ± 0.60.3 ± 0.8
Table 3 Statistical significance of gastroesophageal reflux parameters between patients with and without hiatus hernia in Table 2
REPRPhRPhRE
% time of reflux
24-h> 0.05> 0.05> 0.05> 0.05
Upright> 0.05> 0.05> 0.05> 0.05
Supine> 0.05> 0.05> 0.05> 0.05
No. of episodes
24-h> 0.05> 0.05> 0.05> 0.05
Upright> 0.05> 0.05> 0.05> 0.05
Supine> 0.05> 0.05> 0.05> 0.05
No. of episodes > 5 min
24-h> 0.05> 0.05> 0.05> 0.05
Upright> 0.05> 0.05> 0.05> 0.05
Supine> 0.05> 0.05> 0.05> 0.05