Breast cancer metastasizing to the stomach mimicking primary gastric cancer: A case report

Table 1 Clinical characteristics of representative gastric metastasis of breast cancer

Ref.	Age	Duration after initial diagnosis	Clinical presentation	Endoscopy	Pathology	IHC			Surgery	Treatment	Other metastases site	Overall survival
						ER	PR	C-erbB2
Our case	65	4	Epigastric Discomfort	Diffuse infiltrative mucosal lesion	ILC	neg	neg	pos	No		Bone	-
			Indigestion	Extensive nodular thickening
Pera et al[18]	45	7	Epigastric pain	Erosion of gastric wall	ILC	pos	pos	-	Subtotal gastrectomy	H	-	-
			heart burn
Jones et al[2]	51	3	No symptom	Polyp at antrum wall	ILC	neg	neg	neg	Total gastrectomy	Palliative	Bone	-
	61	6.9	Dysphagia	Fungating mass	ILC	pos	pos	neg	No	C,R	Brain, bone, pleura	-
			weight loss
Eo et al[11]	48	9	Nausea	Elevated mucosal lesion	IDC	pos	pos	neg	No	C	Liver, bone, pleura	-
			anorexia
Arrangoiz et al[8]	70	1	Diarrhea	Mucosal thickening	ILC	pos	neg	neg	No	H	Lung, rectum	-
			constipation
Koike et al[16]	42	5	Epigastric pain	Mucosal erosion	ILC	pos	pos	neg	No	C	-	-
	54	6	Epigastric pain	Mucosal erosion	ILC	pos	pos	neg	No	C, H	Liver, bone, peritoneum	5
	54	3	Epigastric pain	Submucosal tumor	IDC	pos	pos	pos	No	C	Bone	2.3
			vomiting
Geredeli et al[12]	47	3	Increased serum CEA, CA15-3		ILC	neg	neg	neg	Subtotal gastrectomy	C	Bone	-
Buka et al[9]	58	1.2	Abdominal pain	Polypoid infiltration	ILC	pos	pos	neg	Total gastrectomy	C, R	Colon, pleura	7.2
			weight loss
Lee et al[17]	48	5.7	Melena	Mucosal erosion	-	-	-	-	-	C	Bone, liver	-
Yim et al[19]	48	Initial diagnosis	Epigastric discomfort	Mucosal erosion	ILC	neg	neg	-	No	C	Bone	-
Jeon et al[14]	49	5	Melena	Volcano shaped ulcers	IDC	pos	neg	-	No	C	Bone
Kim et al[15]	53	10	Dyspepsia	Mucosal erosion	IDC	neg	neg	-	No	C, H	Kidney, ovary, colon, bone, peritoneal LN	2.4
			lower abdominal pain
			small caliper of stool
Hwang et al[13]	66	17	Back pain	Flat mucosal lesion	ILC	neg	pos		endoscopic mucosal resection	C	Bone	-
Cheoi et al[10]	56	4	Upper abdominal discomfort	Mucosal erosion	IDC	neg	pos	pos	-	C, H	-	1.3
Yu et al[3]	63	10	Melena	Linitis plastica	ILC	pos	pos	pos	No	C, H	Colon, bone marrow	-
			small caliper of stool	flat ulcer

ILC: Invasive lobular carcinoma; IDC: Invasive ductal carcinoma; IHC: Immunohistochemical stain; pos: Positive; neg: Negative; C: Chemotherapy; H: Hormonal treatment.