Anaplastic carcinoma of the pancreas: Case report and literature review of reported cases in Japan

Table 1 Characteristics of patients with anaplastic carcinoma of the pancreas reported in Japan

Variables		n (%)
Sex	Male : Female	38 (63) : 22 (37)
Tumor location	Ph	32 (53)
	Pb and/or Pt	25 (42)
	Entire pancreas	3 (5)
Anemia (hemoglobin level < 10.0 g/dL)		12 (20)
Elevated leucocyte count (> 12000/mm3)		12 (20)
Elevated serum CA19-9 level (> 37 U/mL)		33 (55)
Radiological findings	Tumor/rim enhancement	49 (82)
	Cyst-like appearance	28 (47)
Macroscopic findings	Hemorrhagic necrosis	46 (77)
	Cyst formation	20 (33)
Lymph node metastases (n = 45 with relevant data)		18 (45)
UICC TNM stage	IA	1 (2)
(n = 48 with relevant data)	IB	6 (13)
	IIA	19 (40)
	IIB	16 (33)
	IV	6 (12)
Histological subtype
Giant cell type		11 (18)
Pleomorphic type		18 (30)
Spindle cell type		10 (17)
GCOC type		21 (35)
Recurrence site	Liver	23 (68)
(n = 34 with relevant data)	Local site	10 (29)
	Peritoneum	8 (23)
	Lymph node	7 (21)
< 1-yr survivor (n = 57 with relevant data)		29 (57)
Giant cell type (n = 11)		7 (64)
Pleomorphic type (n = 18)		13 (72)
Spindle cell type (n = 10)		7 (70)
GCOC type (n = 18)		2 (11)
5-yr survivor (n = 57 with relevant data)		7 (12)
Giant cell type (n = 11)		0 (0)
Pleomorphic type (n = 18)		4 (22)
Spindle cell type (n = 10)		1 (10)
GCCO type (n = 18)		2 (11)

CA19-9: Carbohydrate antigen 19-9; GCCO: Giant cell carcinoma of osteoclastoid; Ph: Pancreatic head; Pb: Pancreatic body; Pt: Pancreatic tail.