Case Report
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 14, 2016; 22(38): 8631-8637
Published online Oct 14, 2016. doi: 10.3748/wjg.v22.i38.8631
Anaplastic carcinoma of the pancreas: Case report and literature review of reported cases in Japan
Sojun Hoshimoto, Junichi Matsui, Ryohei Miyata, Yutaka Takigawa, Jun Miyauchi
Sojun Hoshimoto, Junichi Matsui, Ryohei Miyata, Yutaka Takigawa, Department of Surgery, Tokyo Dental College Ichikawa General Hospital, Chiba 272-8513, Japan
Jun Miyauchi, Department of Pathology, Tokyo Dental College Ichikawa General Hospital, Chiba 272-8513, Japan
Author contributions: Hoshimoto S and Matsui J designed the report; Matsui J and Miyata R were in charge of the treatment of the patient and contributed to the collection of clinical data; Hoshimoto S analyzed the data and wrote the manuscript; Matsui J and Takigawa Y reviewed and edited the manuscript; and Miyauchi J reviewed the pathological findings and prepared the pathological images.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Tokyo Dental College Ichikawa General Hospital.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sojun Hoshimoto, MD, PhD, Department of Surgery, Tokyo Dental College Ichikawa General Hospital, 5-11-13 Sugano, Ichikawa-shi, Chiba 272-8513, Japan. sojunh@yahoo.co.jp
Telephone: +81-47-3220151 Fax: +81-47-3248539
Received: May 6, 2016
Peer-review started: May 8, 2016
First decision: June 20, 2016
Revised: July 5, 2016
Accepted: July 31, 2016
Article in press: August 1, 2016
Published online: October 14, 2016
Core Tip

Core tip: Anaplastic carcinoma of the pancreas (ACP), an uncommon histologic subtype of pancreatic cancer, is well known to be associated with more aggressive tumor behavior and less favorable prognosis than conventional pancreatic ductal adenocarcinoma. However, the literature on ACP has been very limited, and its clinicopathological features, therapeutic management, and clinical outcome remain uncertain. We report a case of ACP showing cyst formation and review 60 cases of ACP reported in Japan to elucidate the clinical and radiological features of ACP. This literature review describes the greatest number cases of ACP of any report to date.