Different roles of capsule endoscopy and double-balloon enteroscopy in obscure small intestinal diseases

Table 1 Differences between the definite diagnosis cases between capsule endoscopy and double-balloon enteroscopy

Etiology	Tumor(18)	Ulcer(6)	Diverticulum with a bleeding ulcer (7)	Vascular malformation (19)	Hemangioma (3)	Inflammtory or hyperplastic polyps (7)	Parasites (2)
CE (+)	10	5	1	14	0	5	2
CE (-)	8	1	6	5	3	3	0
DBE (+)	17	2	7	10	3	6	0
DBE (-)	1	4	0	9	0	2	2
P vaule	0.018	0.242	0.005	0.179	-1	1.0	-1

¹Because of too few cases, the statistical calculation yields no significance. CE: Capsule endoscopy; DBE: Double-balloon enteroscopy.

Table 2 Eighteen cases with possible but not confirmed diagnoses

Etiology (cases)	Active bleeding (4)	Vascular malformations (10)	Submucosal bulge (4)
CE(+)	4	8	4
CE(-)	0	2	0
DBE(+)	2	4	1
DBE(-)	2	6	3
P value	0.429	0.170	0.143

CE: Capsule endoscopy; DBE: Double-balloon enteroscopy.

Table 3 Etiologies classified according to the patients’ age (Kruskal-Wallis test, χ² = 22.146, P = 0.008)

Etiology	15-25 yr	25-50 yr	>50 yr
(cases)	16	22	41
Ulcer	2	1	3
Small intestinal	0	1	5
cancer
Stromal tumor	2	5	5
Inflammatory hyperplasia or polyps	2	4	1
Vascular malformations	2	5	22
Active bleeding	1	0	3
Diverticulum with a bleeding ulcer	4	2	1
Hemangioma	1	1	1
Parasites	1	1	0
Submucosal bulge?	1	2	1