Effect of intra-arterial infusion with triolein emulsion on rabbit liver

Table 1 Data of aspartate aminotransferase and alanine aminotransferase in groups 1, 2 and 3

Rabbit	AST, IU/L					ALT, IU/L
No.	Pre	2 h	D1	D4	D7	Pre	2h	D1	D4	D7
Group 1 (n = 9)
Mean ± SD	46.33 ± 13.86	61.78 ± 20.50	124.33 ± 71.68	30.56 ± 5.36	58.56 ± 21.86	58.78 ± 23.66	59.67 ± 21.15	116.56 ± 53.35	75.78 ± 30.65	30.65 ± 15.45
Group 2 (n = 11)
Mean ± SD	45.58 ± 9.11	50.08 ± 13.13	44.42 ± 16.97	31.18 ± 11.99	37.18 ± 10.01	38.50 ± 14.39	38.00 ± 13.62	57.92 ± 19.96	46.82 ± 16.19	43.73 ± 12.72
Group 3 (n = 5)
Mean ± SD	38.20 ± 9.68	39.40 ± 6.07	45.80 ± 23.41	53.80 ± 19.97	63.20 ± 4.97	52.20 ± 4.21	53.80 ± 6.38	60.20 ± 11.14	62.60 ± 7.16	63.80 ± 13.05

Group 1: Hepatic artery group; Group 2: Portal vein group; Group 3: Control group; D: The day after triolein emulsion was injected into the hepatic artery in group 1 and into the portal vein via the superior mesenteric artery in group 2, while D in group 3 represents the day after normal saline was injected into the hepatic artery; pre: Before triolein emulsion was injected into the hepatic vessels of a rabbit.AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; IU: International units.

Table 2 Group 1, 2, and 3 aspartate aminotransferase median and interquartile range and statistical analysis

	AST, IU/L	Median, IU/L	Interquartile range, IU/L
Group 1 (n = 9) P = 0.0016	2 h	18.00	-5.00-31.00
	D1	90.001	16.00-113.00
	D4	-14.00	-28.00-(-4.50)
	D7	6.00	-6.00-30.50
Group 2 (n = 11) P = 0.0095	2 h	6.00	-5.00-8.00
	D1	-3.00	-11.00-18.00
	D4	-14.001	-21.00-(-8.00)
	D7	-8.00	-11.00-(-3.00)
Group 3 (n = 5) P = 0.0355	2 h	1.00	-3.00-5.50
	D1	0.00	-3.50-22.50
	D4	13.00	3.00-29.50
	D7	31.001	13.00-34.00

¹Statistical significance at day 1 in group 1 (90.00 IU/L, P = 0.0016 vs control group) and at day 4 in group 2 (-14.00 IU/L, P = 0.0095 vs control group). Group 1: Hepatic artery group; Group 2: Portal vein group; Group 3:Control group; D represents the day after triolein emulsion in group 1 and after normal saline in group 3 was injected into the hepatic artery of a rabbit, while D in group 2 represents the day after triolein emulsion was injected into the portal vein via the superior mesenteric artery of a rabbit. The group 3 shows statistical significance at day 7 (P = 0.0355). AST: Aspartate aminotransferase.

Table 3 Group 1, 2, and 3 alanine aminotransferase median and interquartile range and statistical analysis

	ALT, IU/L	Median, IU/L	Interquartile range, IU/L
Group 1	2 h	1.00	-5.50- 5.00
(n = 9)	D1	56.001	29.50-84.00
P < 0.0001	D4	20.00	4.00-34.00
	D7	3.00	-7.00-10.50
Group 2	2 h	0.00	-4.00-3.00
(n = 11)	D1	16.001	12.00-31.00
P < 0.0001	D4	6.00	3.00-11.00
	D7	4.00	3.00-11.00
Group 3	2 h	1.00	-1.00-4.50
(n = 5)	D1	4.00	2.00-16.00
P > 0.05	D4	7.00	4.00-18.50
	D7	6.00	2.50-23.50

¹Statistical significance at day 1 in group 1 (56.00 IU/L, P < 0.01 vs control group) and group 2 (16.00 IU/L, P < 0.01 vs control group).Group 1: Hepatic artery group; Group 2: Portal vein group; Group 3: Control group; D represents the day after triolein emulsion in group 1 and normal saline in group 3 was injected into the hepatic artery of a rabbit; D in group 2 represents the day after triolein emulsion was injected into the portal vein via the superior mesenteric artery of a rabbit. The group 3 (control group) shows no significant difference (P > 0.05, not significant) at each time after saline injection. ALT: Alanine aminotransferase.