Adjuvant surgery for advanced extrahepatic cholangiocarcinoma

Table 1 Cases of advanced bile duct cancer treated with adjuvant surgery following effective chemotherapy

Ref.	Diagnosis	Metastasis/invasion	Chemotherapy regimen	Response
Slupski et al[18]	IntraHepatic cholangiocarcinoma	Lung metastases	CDDP, 5-FU, IFN, doxorubicin	PR
Shirabe et al[19]	Gallbladder cancer	Para-aortic LNs	GEM, CDDP, 5-FU	PR
Kitajima et al[20]	Gallbladder cancer	Dissemination	S-1	CR
Morimoto et al[21]	Gallbladder cancer	Liver metastasis	GEM	CR
Kanaji et al[22]	IntraHepatic cholangiocarcinoma	Dissemination	S-1	CR
Kim et al[23]	IntraHepatic cholangiocarcinoma	Portal vein invasion	GEM	PR
Ohno et al[24]	Ampulla of vater cancer	Liver metastasis	GEM, S-1	CR
Hasegawa et al[25]	Gallbladder cancer	Hepatic invasion	S-1, para-aortic LN	PR
Kato et al[17]	Intrahepatic cholangiocarcinoma	Hepatic vein invasion	GEM	SD
	Intrahepatic cholangiocarcinoma	Hepatic vein invasion	GEM	PR
	Intrahepatic cholangiocarcinoma	Arterial invasion	GEM	SD
	Intrahepatic cholangiocarcinoma	Insufficient remnant liver volume	GEM	PR
	Gallbladder cancer	Arterial invasion	GEM	SD
	Gallbladder cancer	Arterial invasion	GEM	PR
	Gallbladder cancer	Arterial invasion portal vein invasion	GEM	SD
	Gallbladder cancer	Arterial invasion	GEM	SD

CDDP: Cisplatin; 5-FU: Fluorouracil; IFN: Interferon; PR: Partial response; CR: Complete response; GEM: Gemcitabine; LN: Lymph node; SD: Stable disease.