Esophagogastroduodenoscopy with conscious sedation does not interfere with catheter-based 24-h pH monitoring

Table 1 Comparisons of baseline data and data obtained during the first 4 h between patients in group A and group B

Variables	Group A(n = 36)	Group B(n = 14)	P value1
Baseline data
Age (yr)	49.5 ± 13.2	49.9 ± 11.0	0.91
Sex (F)	15 (41.7)	5 (35.7)	0.70
Body mass index	22.8 ± 3.2	23.3 ± 3.4	0.75
Presence of heartburn or regurgitation	13 (36.1)	7 (50)	0.37
Erosive esophagitis on EGD	6 (16.7)	2 (14.3)	1
Reflux symptom index	15.9 ± 7.5	16.8 ± 9.2	0.62
Reflux findings score	8.1 ± 3.7	6.4 ± 2.4	0.19
Positive for LPR	12 (33.3)	5 (35.7)	0.87
Positive for pathologic GER	3 (8.3)	1 (7.1)	1
Data obtained during the first 4 h
Frequency of symptoms onset (episodes/h)	0.04 ± 0.1	0.14 ± 0.22	0.08
Pharyngeal probe
Total time of pH < 4 (%)	0.03 ± 0.10	0.07 ± 0.16	0.32
Mean frequency of reflux (episodes/h)	0.07 ± 0.23	0.18 ± 0.47	0.33
Patients with long reflux	0	0	1
Esophageal probe
Total time of pH < 4 (%)	0.96 ± 1.89	0.42 ± 0.81	0.59
Mean frequency of reflux (episodes/h)	0.74 ± 1.51	0.63 ± 0.97	0.49
Patients with long reflux	1 (2.8)	0	1

Data are expressed as absolute numbers (percentage) or mean ± SD.

¹Statistical significance was defined as a P < 0.05. EGD: Esophagogastroduodenoscopy; LPR: Laryngopharyngeal reflux; GER: Gastroesophageal reflux.

Table 2 Comparisons between Period I and Period II in group A patients (mean ± SD)

Variables	Period I	Period II	P value1
Frequency of symptom (episodes/h)	0.04 ± 0.10	0.03 ± 0.06	0.29
Pharyngeal probe
Total time of pH < 4 (%)	0.03 ± 0.10	0.23 ± 0.85	0.21
Mean frequency of reflux (episodes/h)	0.07 ± 0.23	0.29 ± 0.98	0.22
Patients with long reflux	0	0	1
Esophageal probe
Total time of pH < 4 (%)	0.96 ± 1.89	1.11 ± 2.57	0.55
Mean frequency of reflux (episodes/h)	0.74 ± 1.51	0.81 ± 1.76	0.55
Patients with long reflux	1 (2.8%)	5 (13.9%)	0.22

¹Statistical significance was defined as a P < 0.05.