Diagnosis of intestinal tuberculosis using a monoclonal antibody to Mycobacterium tuberculosis

Table 1 Clinical, laboratory and bacteriologic findings in patients with intestinal tuberculosis

Case	Age/gender	Underlying disease	Symptoms	Chest radiograph	Sputum ZN stain	Sputum culture	Sputum PCR	TST	QFT
1	38/F	Epilepsy	Fever	Active TB	+	-	+	+	ND
2	66/F	Lumber neuralgia	Diarrhea	Normal	-	-	-	+	ND
3	81/F	Cecal cancer	Diarrhea, weight loss	Active TB	+	-	-	ND	ND
4	72/M	Post-herpes neuralgia	Abdominal pain	Normal	-	-	-	+	+
5	43/M	Diabetes mellitus	Diarrhea	Normal	-	-	-	-	ND
6	76/M	Gout	Diarrhea	Normal	-	-	-	+	+
7	58/M	Ulcerative colitis	Diarrhea	Normal	-	-	-	-	-
8	74/F	Gastric ulcer	Weight-loss	Active TB	+	-	-	+	+
9	74/F	Colonic polyp	None	Normal	-	-	-	ND	+
10	70/F	Rectal cancer	Diarrhea	Inactive TB	-	-	-	+	ND

TB: Tuberculosis; ZN: Ziehl-Neelsen; PCR: Polymerase chain reaction; TST: Tuberculin skin test; ND: Not determined; QFT: QuantiFERON-TB gold test; M: Male; F: Female.

Table 2 Colonoscopic, bacteriologic and histopathological findings in patients with intestinal tuberculosis

Case	Type	Colonoscopic or macroscopic findings			Histopathological findings
		Location	PV, PD, AMA	AFB in ZN staining	Culture/PCR	Granuloma	TB by IHC staining
1	1	TI, C, A	PV, AMA	-	-	-	-
2	1	TI, C, A	PV, AMA	-	-	+	+
3	1	TI	-	-	-	+	+
4	1	C, A	PV, PD, AMA	-	-	-	-
5	1	TI, C, A, T, D, S	PV, PD, AMA	-	-	-	-
6	1	TI	-	-	-	-	-
7	1	TI, C, A, T, D, S	PV, PD, AMA	-	-	-	-
8	1	TI, C	PV, AMA	-	-	+	+
9	1	TI, C, A, S	PD, AMA	-	-	-	-
10	1	TI	-	-	-	+	+

TI: Terminal ileum; C: Cecum; A: Ascending colon; T: Transverse colon; D: Descending colon; S: Sigmoid colon; PV: Patulous ileocecal valve; PD: Pseudodiverticular deformity; AMA: Atrophic mucosal area; AFB: Acid-fast bacilli; ZN: Ziehl-Neelsen; PCR: Polymerase chain reaction; IHC: Immunohistochemical; TB: Tuberculosis.