Mallory-Denk Bodies in chronic hepatitis

Table 1 Analysis of our 258 patients for Mallory-Denk Bodies and staging of the disease n (%)

	No. of pts	MDB (+)pts	Staging1 in pts with MDB	Comment
NASH	50	10 (20)	Mild in 60% and moderate in 40%	MDB observed in every stage of NASH, predominantly in zone 3
Alcoholic (ASH)	10	5 (50)	Mild in 40% and moderate in 60%	MDB observed in every stage, predominantly in zone 3
PBC	50	11 (22)	Mild in 10%, moderate in 70%, and cirrhosis in 20%	Frequently seen in later stages with predominantly in zone 1
WD	20	16 (80)	Moderate and severe in 60% and cirrhosis in 40%	Frequently seen in later stages with predominantly in zone 1
Hep B	48	3 (6)	Mild in 66% and severe in 34%	Mild case with steatosis
Hep C	50	7 (14)	Mild in 40% and moderate in 60%	MDB observed in every stage
HCC	30	3 (10)		Two cases with Hep B
Total	258	55 (21)

¹Mild: Stage 1; Moderate: Stage 2-3; Severe: Stage 4, and cirrhosis. MDB: Mallory-Denk Bodies; ASH: Alcoholic steatohepatitis; NASH: Nonalcoholic steatohepatitis; PBC: Primary biliary cirrhosis; WD: Wilson disease; HCC: Hepatocellular carcinoma; pts: Patients.