Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 28, 2011; 17(16): 2131-2136
Published online Apr 28, 2011. doi: 10.3748/wjg.v17.i16.2131
Table 1 Baseline characteristics of cases and controls n (%)
CharacteristicsCases (n = 241)Controls (n = 273)P
Sex (male)181 (75.1)193 (70.7)0.43
Age (yr)57.9 ± 12.956.9 ± 14.10.52
Smoking61 (25.3)39 (14.3)0.014
Residence (rural)111 (46.1)142 (52.0)0.32
Hypertension21 (8.7)28 (10.3)0.58
Diabetes15 (6.2)22 (8.1)0.51
Table 2 Genotype of Ku80 G-1401T polymorphism in cases and controls n (%)
GenotypeCasesControl
GG158 (65.6)207 (75.8)
GT55 (22.8)48 (17.6)
TT28 (11.6)18 (6.6)
Table 3 Allele distribution of Ku80 G-1401T polymorphism in cases and controls n (%)
AlleleCasesControls
G371 (77.0)462 (84.6)
T111 (23.0)84 (15.4)
Table 4 Stratification analyses of the association between Ku80 polymorphism and risk of gastric cancer n (%)
VariableCases (n = 241)
Controls (n = 273)
Adjusted OR (95% CI)1P
GGGT + TTGGGT + TT
Age (yr) (median)
< 5876 (62.3)46 (37.7)109 (76.8)33 (23.2)1.97 (1.05-2.90)0.01
≥ 5882 (68.9)37 (31.1)98 (74.8)33 (25.2)1.31 (0.88-1.96)0.3
Sex
Male118 (65.2)63 (34.8)149 (77.2)44 (22.8)1.81 (1.28-2.52)0.01
Female40 (66.7)20 (33.3)58 (72.5)22 (27.5)1.33 (0.81-2.24)0.46
Smoking status
Smokers39 (63.9)22 (36.1)32 (82.1)7 (17.9)2.52 (1.25-5.18)0.051
Non-smokers119 (66.1)61 (33.9)175 (74.8)59 (25.2)1.48 (1.08-2.02)0.054
Residence
Urban85 (65.4)45 (34.6)102 (77.7)29 (22.3)1.88 (1.26-2.76)0.025
Rural73 (65.8)38 (34.2)105 (73.9)37 (26.1)1.48 (0.99-2.15)0.16