How we can improve patients’ comfort after Milligan-Morgan open haemorrhoidectomy

Table 1 Demographic data in Diosmin and control groups

	Diosmin group1 (n = 43)	Control group2 (n = 43)	P value
Mean age( yr)	53.2 (11.2)	51.3 (10.4)	0.6332
Male/female ratio	26/17	24/19	0.6620
No. of resected hemorrhoids	3.4 ± 0.4	3.8 ± 0.5	0.1522
Grades III/IV hemorrhoids	33/10	29/14	0.9247
Mean duration of hemorrhoidal disease (mo)	21.6 (12.6)	22.8 (14.5)	0.6821
Operating time (min)	15.8 (1.9)	16.9 (1.5)	0.1295
No. of constipation	28	26	0.8235

¹Patients treated with Diosmin;

²Patients treated with placebo drug.

Table 2 Postoperative course of Diosmin and control groups

	Diosmin group1 (n = 43)	Control group2 (n = 43)	P value
Median hospital stay (d)	6.1 ( 1.3)	7.3 (3.4)	0.0306
Median time to first bowel action (h)	48 (4.2)	56 (4.6)	0
Median No. of bowel actions in the first week	9 (2.3)	14 (3.1)	0

¹Patients treated with Diosmin;

²Patients treated with placebo drug.

Table 3 Postoperative symptoms of Diosmin and control groups n (%)

	Diosmin group1(n = 43)	Control group2(n = 43)	P value
Minor bleeding
At 2 wk	3 (6.97)	11 (25.58)	0.0409
At 8 wk	2 (4.65)	3 (4.64)	0.6449
Heaviness
At 2 wk	4 (9.30)	14 (32.56)	0.0171
At 8 wk	2 (4.65)	8 (18.60)	0.0436
Pruritus
At 2 wk	9 (20.93)	18 (41.86)	0.0365
At 8 wk	3 (6.97)	10 (23.25)	0.0351
Mucosal discharge
At 2 wk	7 (16.28)	11 (25.58)	0.2890
At 8 wk	2 (4.64)	4 (9.30)	0.3972

¹Patients treated with Diosmin;

²Patients treated with placebo drug.