Indicators of prognosis after liver transplantation in Chinese hepatocellular carcinoma patients

Table 1 Clinical data for 148 patients

	n (%)
Sex
Male	133 (89.9)
Female	15 (10.1)
Age (yr)	Range 17-68 (median 45)
Etiology
Hepatitis B	137 (92.6)
Hepatitis B, C	2 (1.4)
Alcoholic	1 (0.7)
Idiopathic	8 (5.4)
Pre-transplantation AFP (ng/mL)
≤ 400	60 (40.5)
> 400	88 (59.5)
Child–Pugh Class
A	76 (51.4)
B	57 (38.5)
C	15 (10.1)
Meld score
< 14	107 (72.3)
≥ 14	41 (27.2)
Pre-transplantation therapy
Positive	47 (31.7)
Negative	101 (68.2)
Tumor stage	pTNM
I	27 (18.2)
II	40 (27.0)
IIIa	66 (44.6)
IIIb	10 (6.8)
IIIc	5 (3.4)

Table 2 Pathological data from 148 HCC patients

Characteristics	n (%)
Tumor
≤ 3	101 (68.2)
> 3	47 (31.8)
Total tumor size (cm)
≤ 5	24 (16.2)
5–9	30 (20.9)
> 9	94 (63.5)
Lobar distribution
Unilobar	80 (54.1)
Bilobar	68 (45.9)
Differentiation
Well	35 (23.6)
Moderate	100 (67.6)
Poor	13 (8.8)
Vascular invasion
None	47 (31.8)
Micro	49 (33.1)
Macro	52 (35.1)
Lymph node status
Negative	143 (96.6)
Positive	5 (3.4)
Cirrhosis
Negative	13 (8.8)
Positive	135 (91.2)

Table 3 Univariate analysis of all variables that significantly affected tumor-free survival

Predictors	Relative risk	95% CI	P
Total tumor size ( ≤ 9 cm vs > 9 cm)	2.291	1.654-3.173	0.000
Tumor number ( ≤ 4 vs > 4)	1.127	1.052-1.207	0.003
Bilobar disease	2.206	1.327-3.666	0.002
Macrovascular invasion	2.951	2.160-4.032	0.000
Microvascular invasion	4.479	2.126-9.436	0.000
Positive lymph nodes	12.472	4.457-34.898	0.000
Differentiation	1.641	1.014-2.654	0.044
Capsule invasion	1.462	1.092-1.957	0.011