Brief Article
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Mar 14, 2009; 15(10): 1259-1263
Published online Mar 14, 2009. doi: 10.3748/wjg.15.1259
Table 1 Modulating effect of antisense expression of protein kinase Cα on resistance to DOX in multi-drug resistant SGC7901 cells
Cell linesIC50 of DOX (&mgr;mol/L)Resistance index (RI)
SGC79010.076 ± 0.00741.0
SGC7901/VCR2.4 ± 0.14b31.6
SGC7901/VCR/neo2.3 ± 0.19b30.3
SGC7901/VCR/aPKC0.58 ± 0.076b7.6