Survivin expression in early hepatocellular carcinoma and post-treatment with anti-cancer drug under hypoxic culture condition

Table 1 Characteristics of the patients undergoing tumor biopsies (n = 17)

Features	Values
Age, yr	68 (56-81)
Sex (Male/Female)	11/6
AFP (ng/mL)	21 (3-444)
HBsAg/HCVAb	3/14
Tumor size (mm)	15 (8-23)
Cirrhosis (positive/negative)	5/12
Differentiation (well/moderate)	11/6

Data are expressed as the medians with ranges in parentheses unless indicated otherwise. HBsAg: Anti-hepatitis B surface antigen; HCVAb: Anti-hepatitis C antibody; Well: Well-differentiated HCC; Moderate: Moderate-differentiated HCC; Normal ranges: AFP (alpha-feto protein) > 20 ng/mL.

Table 2 PCR primer sequences

Name	Forward sequence (5'-3')	Reverse sequence (5'-3')
Survivin	GCCCAGTGTTTCTTCTGCTT	GCACTTTCTTCGCAGTTTCC
β-actin	AGCCATGTACGTAGCCATCC	AAGTGGTGGTGTCGACTCTC