Protective effects of non-mitogenic human acidic fibroblast growth factor on hydrogen peroxide-induced damage to cardiomyocytes in vitro

Table 1 Viability of cardiomyocytes

	Concentration
Group (n = 8)	of H2O2 (mmol/L)	A570 nm (mean±SD)
Normal	0	0.162±0.007
1	0.075	0.153±0.016
2	0.15	0.121±0.017a
3	0.3	0.098±0.012b
4	0.6	0.0798±0.006d

^aP<0.05, ^bP<0.01, ^dP<0.001 vs normal group.

Table 2 Protective effect of nm-haFGF on the cardiomyocytes exposed to H₂O₂ (mean±SD)

Group	H2O2 concentration	Nm-haFGF	MDA	SOD
	(mmol/L)	(ng/mL)	(nmol/L)	(nU/mL)
Normal			0.388±0.145	0.948±0.034
Positive	0.15		0.602±0.122b	0.612±0.045b
1	0.15	10	0.583±0.052	0.651±0.055
2	0.15	20	0.510±0.026	0.690±0.049
3	0.15	40	0.452±0.073a	0.779±0.019a
4	0.15	80	0.426±0.085a	0.782±0.027a

^aP<0.05 vs normal group,

^bP<0.01 vs positive group.

Table 3 Influence of nm-haFGF on cardiomyocyte viability (mean±SD)

Group	H2O2 concentration (mmol/L)	Nm-haFGF concentration (ng/mL)	A570 nm
Normal			0.542±0.035b
Control	0.15		0.396±0.113
1	0.15	10	0.407±0.054
2	0.15	20	0.42±0.033
3	0.15	40	0.438±0.021a
4	0.15	80	0.456±0.058a

^aP<0.05,

^bP<0.01 vs control group.