Assessment of resin perfusion in hepatic failure in vitro and in vivo

Table 1 Comparison of transaminase, TB and TBA before and after in vitro resin perfusion (mean ± SD)

	Before absorption	After absorption
ALT(IU/L)	74.17 ± 49.68	47.83 ± 22.33
AST(IU/L)	88.83 ± 45.58	58.33 ± 44.64
TB(mol/L)	518.8 ± 180.27	356.13 ± 162.87a
TBA(mol/L)	157.17 ± 53.53	131.67 ± 34.95

^aP < 0.05, vs before absorption.

Table 2 Comparison of transaminase, TB, and TBA before and after in vivo resin perfusion (mean ± SD)

	Before absorption	After absorption
ALT(IU/L)	270.03 ± 355.54	288.38 ± 314.58
AST(IU/L)	252.50 ± 391.51	224.88 ± 356.79
TB(mol/L)	519.66 ± 209.00	460.80 ± 165.99
TBA(mol/L)	194.88 ± 47.32	166.75 ± 48.98b

^bP < 0.01 vs before absorption.

Table 3 Level of LPS and cytokines before and after in vitro resin absorption (mean ± SD)

	Before absorption	After absorption
LPS (ng/L)	60.35 ± 8.58	32.75 ± 10.14a
TNF-(ng/L)	1.49 ± 1.06	1.04 ± 0.91b
IL-1®(ng/L)	2.61 ± 1.42	1.68 ± 0.92b
IL-6(ng/L)	100.07 ± 10.99	87.64 ± 12.27

^aP < 0.05,

^bP < 0.01 vs before absorption.

Table 4 Level of LPS and cytokines before and after in vivo resin absorption (mean ± SD)

	Per- perfusion	Post- perfusion
LPS(ng/L)	58.64 ± 11.03	36.13 ± 5.24a
TNF-(ng/L)	2.28 ± 0.89	1.69 ± 0.76a
IL-1®(ng/L)	1.98 ± 0.82	1.24 ± 0.88a
IL-6(ng/L)	88.41 ± 24.96	84.85 ± 16.55

^aP < 0.01 vs before absorption.