Analysis of Hp infection detection in 150 cases by 14C-UBT

doi:10.3748/wjg.v4.iSuppl2.121

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Oct 15, 1998 (publication date) through Sep 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 121-121
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.121

Analysis of Hp infection detection in 150 cases by ¹⁴C-UBT

You-Gui Zheng, Dong-Ping Liu, Bao-Yu Fu

You-Gui Zheng, Dong-Ping Liu, Bao-Yu Fu, Digest Department the First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning Province, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. You-Gui Zheng, Digest Department the First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning Province, China

Received: July 7, 1998
Revised: August 16, 1998
Accepted: September 8, 1998
Published online: October 15, 1998

Abstract

AIM: To study the sensitivity, specifity and clinical utility of ¹⁴C urea breathing test of Helicobacter pylori infection.

METHODS: All the 150 cases (40 cases of chronic gastritis, 30 cases of gastric ulcer, 50 cases of duodenal ulcer, 20 cases of gastric carcinoma 8 cases of polypous gastritis, 2 cases of portal hypertensive gastropathy) were examined by fibrogastroscopy and confirmed by biopsy pathology, 15 cases of duodenal ulcer and 5 cases of gastric ulcer were treated with PPI tetratherapy for 1 mo, then a comparison between the pretreatment and posttreatment was made, ¹⁴C-urea was calculated by scintillator.

RESULTS: (1) The Hp infection rates of chronic gastritis duodenal ulcer and gastric ulcer and gastric carcinoma had no difference in statistics with the method of ¹⁴C-UBT. (2) There was no difference of ¹⁴C-UBT radioactivity value between chronic gastritis and duodenal ulcer, (3) Chronic gastritis accompanied with gastric mucosal erosion atrophy and entero-metaplasia was significantly higher than simple chronic gastritis (t < 0.05). (4) After one-month bactericidal treatment the bactericidal rate reached 100%.

CONCLUSION: ¹⁴C-UBT is a sensitive, high effective and specific method for Hp detection.

Key Words: Helicobacter infection/diagnosis; Gastritis; Stomach ulcer; Duodenal ulcer; Stomach neoplasms

Citation: Zheng YG, Liu DP, Fu BY. Analysis of Hp infection detection in 150 cases by ¹⁴C-UBT. World J Gastroenterol 1998; 4(Suppl2): 121-121
URL: https://www.wjgnet.com/1007-9327/full/v4/iSuppl2/121.htm
DOI: https://dx.doi.org/10.3748/wjg.v4.iSuppl2.121

Footnotes

E- Editor: Li RF