Relationship between Helicobacter pylori infection and gastric cancer

doi:10.3748/wjg.v4.iSuppl2.117

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Oct 15, 1998 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 117-117
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.117

Relationship between Helicobacter pylori infection and gastric cancer

Xian-En Yu, Ai-Xiang Zhao, Dai-Lin Wei, Jie-Zhen Du

Xian-En Yu, Ai-Xiang Zhao, Dai-Lin Wei, Jie-Zhen Du, Department of Internal Medicine, People's Hospital of Baise Prefecture, Baise 533000, Guangxi Province, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Xian-En Yu, Department of Internal Medicine, People's Hospital of Baise Prefecture, Baise 533000, Guangxi Province, China

Received: July 5, 1998
Revised: August 14, 1998
Accepted: September 4, 1998
Published online: October 15, 1998

Abstract

AIM: The purpose of this study was to investigate the relationship between Helicobacter pylori (Hp) infection and gastric cancer.

METHODS: Hp in 4 antral bioptic specimens was examined by rapid urease test and serum anti-Hp IgG was screened by enzyme linked immunosorbent assay in 21 chronic superficial gastritis (CSG), 26 duodenal ulcer (DU) and 23 advanced gastric cancer patients (AGC). Gastroscopy and historical examination were carried out in all patients.

RESULTS: Hp infection percent in CSG. DU and AGC was 52.4%, 88.5% and 78.3%, respectively. There was significant difference between CSG and DU about Hp infection (P < 0.01) and there was no difference between CSG and AGC about Hp infection (P > 0.05). Hp infection was higher in gastric adenocarcinoma than in gastric signet-ring celluler cancer (P < 0.05).

CONCLUSION: (1) There was no significant relationship between Hp and AGC. (2) But there was much more relation between Hp and gastric adenocarcinoma.

Key Words: Stomach neoplasms/pathology, Helicobacter pylori, Helicobacter infed, Helicobacter infections, Gastritis

Citation: Yu XE, Zhao AX, Wei DL, Du JZ. Relationship between Helicobacter pylori infection and gastric cancer. World J Gastroenterol 1998; 4(Suppl2): 117-117
URL: https://www.wjgnet.com/1007-9327/full/v4/iSuppl2/117.htm
DOI: https://dx.doi.org/10.3748/wjg.v4.iSuppl2.117

Footnotes

E- Editor: Li RF