Basic Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Nov 14, 2019; 25(42): 6299-6310
Published online Nov 14, 2019. doi: 10.3748/wjg.v25.i42.6299
Figure 2
Figure 2 lncRNAXLOC_001659 downregulates miR-490-5p expression by binding to the miR-490-5p seed region. A: Bioinformatics analysis showed the binding between lncRNA XLOC_001659 and miR-490-5p seed region; B: Relative luciferase activities of the EC9706 and EC-1 cells co-transfected with lncRNAXLOC_001659-WT or lncRNAXLOC_001659-Mut luciferase reporter vector and miR-NC or MiR-490-5p mimics. aP < 0.05 and bP < 0.01; C: RT-qPCR demonstrated a significant increase in relative miR-490-5p expression in the EC9706 and EC-1 cells after si-Lnc transfection. bP < 0.01.